Development of neural network reconstruction algorithm for optical brain imaging

Project type: master student

We recently built first-in-class time-domain near-infrared optical tomography system (TD NIROT). It is has a hand-held design, and can be used in neonatal ICU. Now, we are looking for a new fast image reconstruction technique, which combines a finite element method (FEM) and a neural network.

Goal: pave new ways for semi-real-time TD NIROT tomogram reconstruction.

Key words: newral network, TD NIROT, brain oxygenation.

Date: September 2020


You will analyse the state-of-the-art reconstruction process in NIROT and investigate the ways to facilitate it with the focus on neural network. With the current deterministic approach, it takes 10-15 minutes to produce a tomogram. Our goal is to reduce this time to 1 min.

This project is the first step in a cascade of research. The ultimate goal is to develop new reconstruction algorithm that enables real-time optical tomography, which is hardly needed in neonatal intensive care, and will improve (and save) lives of thousands yearly born extreme preterms.

The project is hosted by Biomedical Optics Research Laboratory (BORL), Dept. of Neonatology, University Hospital Zurich. The lab has an expertise in NIRS and NIROT, including clinical applications. Since we are part of the hospital, we offer insights into clinical everyday life and the true needs of clinicians. In addition, we are an interdisciplinary team with a great spirit that offers you an exciting environment.


  • skills in neural network and data processing,
  • knowledge in NIROT is very welcome as well.

Alexander Kalyanov, E-Mail:, Tel.: 043 253 30 31.

Prof. Martin Wolf
E-Mail: Tel: 044 255 53 46
Biomedical Optics Research Laboratory, Neonatologie, UniversitätsSpital Zürich, 8091 Zürich

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