Pioneer - time-resolved NIROT
New generation time resolved near-infrared
optical tomography setup (TR NIROT), which is based on a time-of-flight 32x32
SPAD camera with high photon detection probability in the NIR range.
Pioneer is the new time-resolved
near-infrared optical tomography (TR NIROT) system, which was designed in BORL.
It aims at brain imaging of preterm neonates with high spatial resolution and
at detecting hypoxia and bleeding.
Pioneer is based on a camera with a high
number (1024) of pixels capable of detecting the time-of-flight of single
photons – Piccolo. The pixels comprise a single-photon avalanche diode (SPAD)
with 116ps time response and an unprecedented sensitivity, i.e. a photon
detection probability, of 12% at 800nm. This camera chip was especially designed
for NIROT applications by BORL and AQUA (Advanced Quantum Architecture
laboratory, School of Engineering, EPFL Lausanne). Pioneer employs a super
continuum laser to generate a narrow-band light at multiple wavelengths. The
light is guided to 11 source fibers, which are hosted in a rigid source ring.
It embedded in soft, biocompatible silicon to provide a gentle contact to
neonatal head. We implement the wavelength normalization to correct for
coupling and surface artifacts. The total number of available source-detector
pairs is greater than 11’000.
- Real time NIROT reconstructions