Herzlich willkommen in der

Team


Leitung Forschung Biomedizinische Optik
(BORL, Biomedical Optics Research Laboratory)



Klinische Forschung Neonatologie

sowie 

Larsson-Rosenquist Stiftung-Professur für Neuroentwicklung, Wachstum und Ernährung des Neugeborenen 







Dr. sc. nat.  -  Leiter Swiss NeoNet
Co-Leitung klinische Forschung
mark.adams@usz.ch
Dr. med. -  Oberarzt
Co-Leitung klinische Forschung
christoph.rueegger@usz.ch
Prof. Dr. med., MSc
dirk.bassler@usz.ch
Prof. Dr. med.
buh@usz.ch
MSc in Molecular & Cellular Biology  -  Doktorandin
stefanie.chie@usz.ch
Administration Swiss NeoNet
tanja.dacunha@usz.ch
MSc in Industrial Physics Engineering  -  Doktorand
aldo.dicostanzomata@usz.ch
Informatiker Swiss NeoNet
johannes.didaskalu@usz.ch
Pflegeexpertin
barbara.dinten@usz.ch
Physiotherapeutin
denise.etzweiler@usz.ch
Prof. Dr. med. -  Leitender Arzt
jean-claude.fauchere@usz.ch
Dr. med.  -  Stationsarzt
vincent.gaertner@usz.ch
Dr. med.  -  wiss. Mitarbeiterin
deborah.gubler@usz.ch
MSc in Computer Science
sabino.guglielmini@usz.ch
Dr. rer. medic. -  Musiktherapeutin
friederike.haslbeck@usz.ch
Dr. med. -  Oberärztin
marianne.hauff@usz.ch
Dr. sc. med.  -  Postdoc
manya.hendriks@usz.ch
Sekretariat LRS Professur G. Natalucci
piroska.herpai@usz.ch
MSc in in Biomedical Engineering ETH
jingjing.jiang@usz.ch
PhD  -  wiss. Mitarbeiter
alexander.kalyanov@usz.ch
Dr. med. -  Oberärztin
tanja.karen@usz.ch
Dr. sc. ETH  -  Postdoc
stefan.kleiser@usz.ch
Eidg. Turn- und Sportlehrerdiplom II ETH
claudia.knoepfli@usz.ch
MSc in Psychologie
brigittemaria.koller@usz.ch
PhD Cell Biology
Laborleitung LRS Professur G. Natalucci
maria.miletta@usz.ch
Prof. Dr. med. -  Leitender Arzt
Larsson-Rosenquist Foundation-Professorship
giancarlo.natalucci@usz.ch
PD Dr. med. -   wiss. Mitarbeiter
mathias.nelle@usz.ch
MSc ETH in Biology  -  PhD student
ThiDao.Nguyen@usz.ch
Diplom-Kaufmann  -  wiss. Mitarbeiter
nitsch@oxyprem.com@usz.ch
Dr. sc. ETH - Postdoc
daniel.ostojic@usz.ch
Dr. rer. nat. -  Psychologe
tilman.reinelt@usz.ch
Dr. med. -  Oberärztin
tanja.restin@usz.ch
Dr. med. -  Oberarzt meV.
manuel.schmid@usz.ch
Dr. sc. nat. -  Postdoc
felix.scholkmann@usz.ch
Ingenieurin FH in Biotechnologie
celine.stutz@usz.ch
Direktionsassistentin - Finanzen Forschung + Personal
iris.suter@usz.ch
Dr. med.  -  Fachärztin
janine.thomann@usz.ch


Projects:

Mark Adams  - Co-Leitung klinische Forschung
Swiss Neonatal Network
Project leader of the Swiss Neonatal Network & Follow-up Group, a national registry for very preterm children. Its purpose is to monitor and research their mortality and morbidities and to generate quality indicators for the Swiss neonatal intensive care units. My main activities are the development and maintanance of the registry; statistical evaluation of the data; organization of the participating committees (Scientific Committee, Neo-Group, Follow-up Group); coordination with the Vermont-Oxford Network, EuroNeoNet and similar national and international organizations; coordination of and participating in epidemiological studies; co-authorship in publications; compilation of quality indicator reports and QI-alert lists.

Dirk Bassler
NEuroSIS see...,  ALBINO see...,  ROPROP see... 

Hans Ulrich Bucher
klinische Forschung

Sefanie Chie
Neurodevelopment, Growth and Nutrition of the Newborn

Tanja da Cunha
Administration Swiss Neonatal Network (Swiss NeoNet)

Aldo di Costanzo
3D TOF Imaging

Johannes Didaskalu
Informatiker Swiss Neonatal Network (Swiss NeoNet)

Barbara Dinten-Schmid
Pflegeexpertin

Denise Etzweiler
General movements assessments from birth to 3 months and neurodevelopmental outcome up to the age of 2 years in infants (GMA Outcome)

Jean-Claude Fauchère
Communication between families and the health care team in perinatal intensive care:
The FamKom study

In this study, we investigate the quality of communication and counselling of health care professionals with parents of seriously ill newborns.

Our aim is to gain a better insight into the counselling process. In particular, we investigate the discussion/communication strategies used by professionals and parents to deal with these situations and the differences and similarities in consultations. In addition, the material is suitable for training purposes and we will develop a flow chart for counselling and the decision-making process.

Vincent Gaertner
SUNSET study: Surfactant nebulization for the early aeration of the preterm lung: A single blinded, parallel, randomized controlled trial

Deborah Gubler
Communication between families and the health care team in perinatal intensive care:
The FamKom study

In this study, we investigate the quality of communication and counselling of health care professionals with parents of seriously ill newborns.

Our aim is to gain a better insight into the counselling process. In particular, we investigate the discussion/communication strategies used by professionals and parents to deal with these situations and the differences and similarities in consultations. In addition, the material is suitable for training purposes and we will develop a flow chart for counselling and the decision-making process.

Sabino Guglielmini
Hyperscanning
Functional near-infrared imaging (fNIRI) hyperscanning is a promising new method able to asses the brain-to-brain coupling during different inter-personal interactions tasks. fNIRI is an optical neuroimaging method that is able to non-invasively measure changes in cerebral oxygenation and haemodynamics in humans while having the advantages of being easily applicable in a natural context and enabling the measurement of physiological signals that cannot be derived by the classical neuroimaging methods such as functional magnetic resonance imaging (fMRI) or electroencephalography (EEG). My project aims to advance fNIRI hyperscanning approach and in particular investigate the quantitative role and relevance of the different communication channels.

Friederike Haslbeck
Music Therapy   (for more information please go to...)

Marianne Hauff
General movements assessments from birth to 3 months and neurodevelopmental outcome up to the age of 2 years in infants (GMA Outcome)

Manya Hendriks
Communication between families and the health care team in perinatal intensive care:
The FamKom study

In this study, we investigate the quality of communication and counselling of health care professionals with parents of seriously ill newborns.

Our aim is to gain a better insight into the counselling process. In particular, we investigate the discussion/communication strategies used by professionals and parents to deal with these situations and the differences and similarities in consultations. In addition, the material is suitable for training purposes and we will develop a flow chart for counselling and the decision-making process.

Jingjing Jiang
NIROT
Tumor oxygenation is one of the important biomarkers for diagnosis of cancer. Tumor hypoxia is often heterogeneous, i.e. showing different oxygenation levels in different parts of a single tumor. However, the lack of non-invasive measurement of distribution of tissue oxygenations sets obstacles to achieve this valuable information successfully.
Near Infrared Optical Tomography (NIROT) shows great potential to image tumor oxygenation levels non-invasively. NIROT is intrinsically sensitive to the quantities of Oxy-haemoglobin (O2Hb) and deoxy-haemoglobin (HHb), two major molecules to determine tissue oxygenation.  Moreover, the use of non-ionizing region of light and harmless intensities gives NIROT the strength to image objects non-invasively and continuously.  My project aims to develop a NIROT system for clinical applications.

Alexander Kalyanov
Dr Alexander Kalyanov studied biochemical physics at Saratov State University. He obtained his PhD in 2011 in the Optics and Biophysics Dept. (OBP) of the same institution. During his PhD, Alexander focused on optical coherence methods in life sciences with a particular focus on full-field optical coherence microscopy. After defense, he continued his research activity in OBP. In 2014, Alexander joined the Biomedical Optics Research Laboratory (BORL) at the University Hospital Zurich as a postdoc, applying his knowledge of optics and biophotonics to Near-Infrared Optical Tomography (NIROT). Now, an associated researcher, Dr. Kalyanov leads a group of several PhD and MS students developing a new time-resolved NIROT system, “Pioneer”, for the imaging of the brains of preterm neonates.

Tanja Karen
Continuous measurement of brain oxygenation, haemodynamics and brain function in preterm infants using near-infrared spectroscopy. The overall aim is to optimize intensive care in preterm infants including cerebral monitoring with NIRS as part of the clinical management and to study brain development which are the keys to reduce mortality and morbidity in this vulnerable and high-risk population.

Stefan Kleiser
UZH BioEntrepreneur-Fellowship “Translating a novel oximeter to clinical use”. At BORL we have developed a highly precise cerebral NIRS oximeter, outperforming the state of the art. Aim of this project is to make OxyPrem available to clinicians and enable them to improve treatment using this technology.

Claudia Knöpfli
Epo Study, Virtopsy, ALBINO see... RopRop see...

Brigitte Koller
Study Nurse Epo Studie

Maria Consolata Miletta
Laborleitung, Neurodevelopment, Growth and Nutrition of the Newborn

Giancarlo Natalucci
- Developmental paediatrics, BrainDNIU study (Impact of intrauterine growth restriction on brain development and consequences for later neurodevelopmental outcome: a prospective cohort study), IUGR (Intrauterine Growth Restriction)
- Larsson-Rosenquist Foundation-Professorship for Neurodevelopment, Growth and Nutrition of the Newborn

Mathias Nelle
Home Transition

Thi Dao Nguyen
Impact of intrauterine growth restriction on brain development and consequences for later neurodevelopmental outcome: a prospective cohort study (BrainDNIU)

Alexander Nitsch
UZH BioEntrepreneur-Fellowship “Translating a novel oximeter to clinical use”. At BORL we have developed a highly precise cerebral NIRS oximeter, outperforming the state of the art. Aim of this project is to make OxyPrem available to clinicians and enable them to improve treatment using this technology.

Daniel Ostojic
develops hard- and software for non-invasive oxygenation monitoring NIRS. Combining design methodologies of user-centered design and design-for-safety, the NIRS as a technology is being gradually brought into neonatal clinical practice.

Tilman Reinelt
Psychologe, Neurodevelopment, Growth and Nutrition of the Newborn

Tanja Restin
The lack of oxygen supply does not only cause encephalopathy, but also contributes to restricted fetal growth and the development of necrotizing enterocolitis. Our goal is to better understand the molecular mechanisms of oxygen sensing and adaptation and to find ways to improve patient outcome.

Christoph Rüegger  - Co-Leitung klinische Forschung
Erythropoietin for repair of cerebral injury in very preterm infants
A first project called "Erythropoietin for repair of cerebral injury in very preterm infants" is a randomized controlled trial which will test the hypothesis that EPO is beneficial when intraventricular haemorrhage (IVH) occurred as suggested by previously published retrospective observational studies. The new "EPO-Repair trial" will only include infants with IVH, and EPO or placebo will be given subsequently. The main endpoint will be neurodevelopmental assessment at 5 years, the second endpoints MRI at term equivalent and neurodevelopmental assessment at 2 years, respectively.
Virtual autopsy or Virtopsy
A second project deals with a new autopsy technique, called "virtual autopsy" or "virtopsy". This minimally invasive autopsy by post mortem cross-sectional imaging has been suggested as an alternative for conventional autopsy in view of the declining consented autopsy rates. With this prospective multidisciplinary investigation we aim to compare the accuracy of this "virtual autopsy" approach using post mortem MR imaging and CT-guided biopsy with that of conventional autopsy in fetuses, neonates and children for detection of the major pathologies and/or determination of the cause of death.
RopRop  see...

Felix Scholkmann
Fields of research: (i) (biomedical) signal processing and data analysis, (ii) biomedical optics (measurement of tissue hemodynamics and oxygenation using near-infrared spectroscopy (NIRS)), (iii) neuroscience and integrative physiology (brain research using NIRS, interaction between brain activity and the autonomic nervous system), (iv) biophysics (ultra-weak photon emission from biosystems). https://felix-scholkmann.com/

Manuel Schmid
Clinical Research and NIRS

Céline Stutz
Neurodevelopment, Growth and Nutrition of the Newborn

Iris Suter
Research Finances, Personnel Management, Web

Janine Thomann
Effect of High Frequency Oscillatory High Flow Nasal Cannula on Desaturations and Bradycardia in Preterm Infants: A Randomized Crossover Trial.

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